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Brand-name vs. compounded GLP-1s: What’s the difference?

GLP-1 medications have changed the conversation around weight management – and for good reason. For many people, they’re a powerful tool to help regulate appetite, improve blood sugar control and support sustainable weight loss. But choosing between brand names and newer, lesser-known compounded versions isn’t always clear.

Understanding how these medications differ, how they’re regulated and what those differences mean for your health can help you make a more informed decision with your provider.

What are GLP-1 medications?

GLP-1 – short for glucagon-like peptide-1 – is a natural hormone your body releases after you eat. It helps regulate appetite, digestion and blood sugar, which all play a big role in how hungry or full you feel.

GLP-1 medications work by activating the same receptors as your body’s natural GLP-1 hormone. Simply put, they help your body better manage hunger cues, feel full sooner and use energy more efficiently – key factors in healthy weight loss.

These medications were originally developed to manage type 2 diabetes, but researchers discovered their powerful impact on appetite and metabolism. Today, many people recognize them by brand names like Ozempic®, Wegovy®, Mounjaro® and Zepbound®.

What’s the difference between brand-name and compounded GLP-1s?

Brand-name GLP-1 medications are approved by the U.S. Food and Drug Administration (FDA) and manufactured under strict quality and safety standards. Compounded GLP-1s, on the other hand, are non-brand-name versions prepared by compounding pharmacies that aren’t affiliated with the original drug manufacturers.

While compounded medications may seem appealing because of their lower prices and easier access during drug shortages, they can come with real safety risks. Unlike name-brand GLP-1s, compounded versions aren’t reviewed by the FDA for safety, quality or effectiveness. This means that dosing, purity, or consistency can vary from batch to batch.

Because of these uncertainties, several leading medical organizations – including the American Diabetes Association and Obesity Medicine Association – have recommended against using non-FDA-approved compounded GLP-1s. The Obesity Action Coalition, a nonprofit focused on patient advocacy, education, and support, has also advised caution.

Why is FDA approval important?

FDA approval adds an important layer of protection for patients. Before a brand-name GLP-1 medication is approved, it goes through extensive clinical trials to confirm that it works the way it’s supposed to, is dosed appropriately and has clearly understood side effects. The FDA also closely reviews how the medication is manufactured to ensure quality from dose to dose.

This level of oversight is a big deal. FDA-approved GLP-1 medications offer reliable dosing, consistent potency, and clear guidance for prescribing and monitoring – so patients and clinicians know what to expect. That consistency helps reduce the risk of unexpected side effects or variations in effectiveness.

What makes GLP-1 care at Indigo different?

If you’re dealing with weight-related health concerns or your provider has recommended weight loss to support your overall health, you don’t have to figure out GLP-1 treatment on your own. Indigo Urgent Care is here to get you started by offering care that’s clear, supportive and centered on you.

 

At Indigo, you can expect:

  • No membership fees. There are no subscriptions or ongoing commitments.
  • 100% virtual care. Same-day and next-day appointments make it easy to fit care into your schedule.
  • Local, licensed clinicians. Indigo is part of MultiCare Health System, so you know you’re working with providers and pharmacies in your community.
  • FDA-approved medications, including pills. Options may include Ozempic®, Wegovy®, Mounjaro®, Zepbound®, or an oral GLP-1, depending on what’s right for you.
  • Flexible payment options. Indigo accepts most insurance plans and offers $99 self-pay visits.

Getting started is simple:

  1. Schedule a virtual appointment.
  2. Meet with a provider for evaluation.
  3. Create a personalized treatment plan.
  4. Receive your GLP-1 medication from the pharmacy of your choice.

Ready to take the next step? Learn more about Indigo’s weight-loss care and book your Virtual Care visit appointment today.

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